ALTERNATIVE CANCER TREATMENTS
Clodronate
If the story of clodronate does not anger you, you are not paying attention.
We mentioned clodronate in our second edition of the Wellness
Directory of Minnesota™, but held off listing it here for the longest time. Why?
Because we cannot get it in
It is nearly 20 years old and is used to fight and reverse osteoporosis. Studies from Europe show it can reverse bone loss and, when mixed with calcium, it will significantly increase lumbar bone density.
Now, if you are paying attention, a majority of breast cancer deaths occur after the cancer has metastasized (spread) to the bones.
Let me quote an article written by the Life Extension Foundation:
The Food and Drug Administration's suppression of clodronate may have caused the premature or needless death of about 30,000 American women each year, based on the Aug. 6, 1998, New England Journal of Medicine study. Since clodronate could have been made available 15 years ago, about 517,000 American breast cancer victims were forced to suffer agonizing bone metastasis, and a total of 450,000 women probably died prematurely because the FDA aggressively denied this drug to cancer patients. |
Clodronate is cheap. It is effective. It has minimal side effects. It does not kill cancer cells. It is used as an adjunct to whatever therapy you are using for the single purpose of preventing bone metastases. It is outlawed in America, though there are some expensive rip-offs that the FDA is pushing (protecting American business interests) that are not as safe and not as effective as clodronate.
Here are some studies of its effectiveness:
1988: breast cancer patients with multiple bone metastasis treated with clodronate experienced fewer fractures and less hypercalcemia, with a higher survival rate and no side effects. [Biomed. Pharmacother. (France), 42/2 (111-1160]
1987: two studies showed that oral clodronate successfully reduced a mean serum calcium concentration in 22 our of 25 patients with various types of malignant tumors, and that clodronate is a valuable clinical tool in the management of patients with malignancy-associated hypercalcemia. [Acta. med. Scand. (Sweden), 221/5 (489-494)]
1985: clodronate given to patients with episodes of hypercalcemia and osteolysis due to carcinoma reduced serum calcium in 14 of 17 episodes and bone resorption in all patients. [Br. J. Cancer (England), 51/5 (665-669)]
1984: published in both France and the US, this study concluded that "Clodronate is very effective against osteoclasts," and "Clodronate may be a useful adjuvant in managing metastatic bone disease." [Presse Med. 13/8, 479-482); New England Journal of Medicine, 308/25 (1499-1501)]
According to the Life Extension Foundation, the standard dose for treating cancer is 800 mg of clodronate taken twice daily, though twice this dosage has been used safely. Breast cancer patients might want to consider a 3 - 5 year regimen on clodronate therapy. Blood tests to measure serum calcium levels and kidney function should be done 10 days after initiating clodronate therapy and every one to two months thereafter. In a small minority of patients, clodronate will cause too much calcium to be pulled from the blood to the bone. If you suffer from severe renal insufficiency (a kidney disorder requiring dialysis) you should not use clodronate, nor should you use clodronate if you are pregnant.
We have found a location in Canada that will sell you clodronate: http://www.lifepharma.com/expl/CLODRON/clodroin.htm. The online store there does not work, so you will have to contact them by email or phone:
ben@uniserve.com
PO Box 550 - Abbotsford, B.C. V2S 5Z5 Canada.
Ph: (604) 856-0171
Additionally, there is a Mexican company with a US postal box and phone number (cost is about a dollar a pill):
Leipzing & Pemebee
Ph: 619-818-7745
e-mail leipzing4090@yahoo.com.
When you order Poly-MVA, they will send you clodronate with your Poly.
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